李子聪 教授
E-Mail:zcli@sdu.edu.cn
个人简介
李子聪,2014年在新加坡国立大学获得博士学位,2014-2018年在中国科学院上海植物逆境生物学研究中心做博士后,主要从事植物表观遗传学机制的研究。现为9159金沙游戏场“杰出中青年”特聘教授,国家高层次青年人才和山东省“杰出青年基金”获得者,山东省植物生理与分子生物学学会理事,博士生导师。 近年来先后在Nature Genetics, Nature Plants, Molecular Plant, Plant Physiology, Trends in Genetics等杂志发表高水平文章十余篇。
研究方向
本课题组以模式植物拟南芥为研究材料,利用细胞学,遗传学,分子生物学,基因组学,生物信息学等研究方法,对植物细胞全能性的表观遗传学机理进行研究。
(1)植物胚胎发育及营养生长过程中细胞全能性随年龄增加而降低的表观遗传机制
(2)染色质装配过程对植物细胞全能性的影响
(3)以细胞全能性为研究对象,揭示植物特异性表观遗传调控机制
(4)组蛋白变体替换及细胞分裂对植物细胞全能性的影响
(5)植物细胞全能性对作物遗传改良的应用
主持项目
2021-2023 山东省杰出青年基金, 主持
2021-2025 9159金沙游戏场杰出中青年学者基金, 主持
2020-2022 国家高层次青年人才项目,主持
2019-2023 国家自然科学基金面上项目,主持
2018-2023 9159金沙游戏场齐鲁青年学者项目,主持
发表文章
Z. Li#, X. Luo#, Y, Ou#, H. Jiao, L, Peng, X. Fu, A. Macho, R. Liu, Y. He. (2021). JASMONATE-ZIM DOMAIN proteins engage Polycomb chromatin modifiers to modulate Jasmonate signaling in Arabidopsis. Molecular Plant 14: 732-747
F. Zhao, H. Zhang, T. Zhao, Z. Li, D. Jiang. (2021) The histone variant H3.3 promotes the active chromatin state to repress flowering in Arabidopsis. Plant Physiology, 86: 2051–2063
H. Jiao, Y. Xie, Z. Li. (2020) Current understanding of plant Polycomb group proteins and the repressive histone H3 Lysine 27 trimethylation. Biochemical SocietyTransactions, 48: 1697-1706
Z. Li, Y. He. (2020) Roles of Brassinosteroids in Plant Reproduction. International Journal of Molecular Sciences, 21(3): 872
Z. Li, X. Fu, Y. Wang, R. Liu, Y. He (2018) Polycomb-mediated gene silencing by the BAH-EMF1 complex in plants. Nature Genetics, 50: 1254–1261.
Z. Li#,D. Jiang#, and Y. He (2018) FRIGIDA establishes a local chromosomal environment for FLOWERING LOCUS C mRNA production. Nature Plants, 4: 836-846.
Z. Li#, D. Jiang#, X. Fu, X. Luo, R. Liu, Y. He (2016) Coupling of histone methylation and RNA processing by the nuclear mRNA Cap-Binding Complex. Nature Plants, 2:16015.
Z. Li#, Y, Ou#, Z. Zhang, J. Li, Y. He (2018) Brassinosteroid signaling recruits histone 3 lysine-27 demethylation activity to FLOWERING LOCUS C chromatin to inhibit the floral transition in Arabidopsis. Molecular Plant, 11: 1135-1146.
W. Yuan, X. Luo, Z. Li, W. Yang, Y. Wang, R. Liu, J. Du, Y. He (2018) A cis cold memory element and a trans epigenome reader mediate Polycomb silencing of FLC by vernalization in Arabidopsis. Nature Genetics, 48:1527-1534.
Y. He and Z. Li (2018) Epigenetic environmental memories in plants: establishment, maintenance and reprogramming. Trends in Genetics, S0168-9525(18)30127-6.
X. Gu, C. Le, Y. Wang, Z. Li, D. Jiang, Y. Wang, Y. He. (2013) Arabidopsis FLC clade members form flowering-repressor complexes coordinating responses toendogenous and environmental cues. Nature communications, 4:1947.
D. Jiang, NC. Kong, X. Gu, Z. Li, Y. He. (2011) Arabidopsis COMPASS-like complexes mediate histone H3 lysine-4 trimethylation to control floral transition and plant development. PLoS Genetics, 7:e1001330.